NAPEPLD antibody (N-Term)

Catalog No. ABIN2786441

Product Details anti-NAPEPLD Antibody

Target: NAPEPLD (N-Acyl Phosphatidylethanolamine phospholipase D (NAPEPLD))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAPEPLD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TWKNPSIPNV LRWLIMEKDH SSVPSSKEEL DKELPVLKPY FITNPEEAGV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NAPE-PLD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NAPE-PLD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 393 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NAPEPLD antibody (ABIN2786441)

Sousa-Valente, Varga, Torres-Perez, Jenes, Wahba, Mackie, Cravatt, Ueda, Tsuboi, Santha, Jancso, Tailor, Avelino, Nagy et al.: "Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related ..." in: The Journal of comparative neurology, Vol. 525, Issue 8, pp. 1778-1796, (2016) (PubMed).

Target Details for NAPEPLD

Target: NAPEPLD (N-Acyl Phosphatidylethanolamine phospholipase D (NAPEPLD))

Alternative Name: NAPE-PLD (NAPEPLD Products)

Synonyms: FMP30 antibody, NAPE-PLD antibody, A530089G06 antibody, Mbldc1 antibody, N-acyl phosphatidylethanolamine phospholipase D antibody, NAPEPLD antibody, Napepld antibody

Background: NAPE-PLD hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. NAPE-PLD is responsible for the generation of anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors
Alias Symbols: DKFZp781D1098, FMP30, NAPE-PLD
Protein Interaction Partner: UBC, PPP1CC,
Protein Size: 393

Molecular Weight: 45 kDa

Gene ID: 222236

NCBI Accession: NM_198990, NP_945341

UniProt: Q6IQ20