GANC antibody (Middle Region)

Catalog No. ABIN2786405

Product Details anti-GANC Antibody

Target: GANC (Glucosidase, Alpha, Neutral C (GANC))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rabbit, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLGFRKEPSS VTTHSSDGKD QPVAFTYCAK TSILSLEKLS LNIATDWEVR

Predicted Reactivity: Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GANC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GANC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 914 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GANC antibody (ABIN2786405)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for GANC

Target: GANC (Glucosidase, Alpha, Neutral C (GANC))

Alternative Name: GANC (GANC Products)

Synonyms: 5830445O15Rik antibody, 9330160A12 antibody, mFLJ00088 antibody, glucosidase alpha, neutral C antibody, calpain-3 antibody, glucosidase, alpha; neutral C antibody, GANC antibody, LOC453361 antibody, ganc antibody, Ganc antibody

Background: GANC has alpha-glucosidase activity.Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138256
Protein Interaction Partner: UBC,
Protein Size: 914

Molecular Weight: 104 kDa

Gene ID: 2595

NCBI Accession: NM_198141, NP_937784

UniProt: Q8TET4