SENP5 antibody (Middle Region)

Catalog No. ABIN2786236

Product Details anti-SENP5 Antibody

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSGFLDEVMK KYGSLVPLSE KEVLGRLKDV FNEDFSNRKP FINREITNYR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SENP5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SENP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 755 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SENP5

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Alternative Name: SENP5 (SENP5 Products)

Synonyms: 6230429P13Rik antibody, A730063F07Rik antibody, AI851888 antibody, BB189556 antibody, SMT3IP3 antibody, SENP5 antibody, Senp5 antibody, senp5 antibody, SUMO1/sentrin specific peptidase 5 antibody, SUMO/sentrin specific peptidase 5 antibody, SUMO1/sentrin specific peptidase 5 L homeolog antibody, SENP5 antibody, Senp5 antibody, senp5 antibody, senp5.L antibody

Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
Alias Symbols: DKFZp564O1016, FLJ42398, MGC27076
Protein Interaction Partner: RABGAP1, SUMO3, PASK, SUMO2,
Protein Size: 755

Molecular Weight: 87 kDa

Gene ID: 205564

NCBI Accession: NM_152699, NP_689912

UniProt: Q96HI0