TRIB2 antibody (Middle Region)
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- Target See all TRIB2 Antibodies
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRIB2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YPFHDIEPSS LFSKIRRGQF NIPETLSPKA KCLIRSILRR EPSERLTSQE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against TRIB2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TRIB2
- Top Product
- Discover our top product TRIB2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 343 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Alternative Name
- TRIB2 (TRIB2 Products)
- Synonyms
- TRIB2 antibody, Trb2 antibody, Xtrbl antibody, gs3955 antibody, c5fw antibody, trb2 antibody, xtrb2 antibody, TRB2 antibody, C5FW antibody, GS3955 antibody, TRB-2 antibody, AW319517 antibody, RGD1564451 antibody, tribbles pseudokinase 2 antibody, tribbles pseudokinase 2 S homeolog antibody, TRIB2 antibody, trib2 antibody, trib2.S antibody, Trib2 antibody
- Background
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TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Alias Symbols: GS3955, TRB2, C5FW
Protein Interaction Partner: RFWD2, SMURF1, BTRC, PRMT6, UBC, RPS6KB1, SLAMF7, APP, UBQLN4,
Protein Size: 343 - Molecular Weight
- 39 kDa
- Gene ID
- 28951
- NCBI Accession
- NM_021643, NP_067675
- UniProt
- Q92519
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