GSPT2 antibody (Middle Region)

Catalog No. ABIN2786166

Product Details anti-GSPT2 Antibody

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Pig, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GANIKEQSDF CPWYTGLPFI PYLDNLPNFN RSIDGPIRLP IVDKYKDMGT

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GSPT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GSPT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 628 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSPT2

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Alternative Name: GSPT2 (GSPT2 Products)

Synonyms: ERF3B antibody, GST2 antibody, G1 to S phase transition 2 antibody, GSPT2 antibody, Gspt2 antibody

Background: GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.
Alias Symbols: FLJ10441, GST2, eRF3b, ERF3B
Protein Interaction Partner: UBC, ATG7, STAT1, SNX2, SNX1, SHMT2, SHMT1, RDX, NASP, IDE, GSPT1, CTTN, ATP6V1C1, UPF1, PABPC1, SMG1, CCT2, APP, UBR5, ETF1,
Protein Size: 628

Molecular Weight: 69 kDa

Gene ID: 23708

NCBI Accession: NM_018094, NP_060564

UniProt: Q8IYD1