SENP3 antibody (N-Term)

Catalog No. ABIN2786148

Product Details anti-SENP3 Antibody

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: PPPKPRLKSG GGFGPDPGSG TTVPARRLPV PRPSFDASAS EEEEEEEEEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SENP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 574 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SENP3

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Alternative Name: SENP3 (SENP3 Products)

Synonyms: SMT3IP1 antibody, SSP3 antibody, Ulp1 antibody, AA408656 antibody, Smt3ip antibody, Smt3ip1 antibody, ssp3 antibody, smt3ip1 antibody, fa03d07 antibody, wu:fa03d07 antibody, senp3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUMO/sentrin specific peptidase 3 antibody, Sumo1/sentrin/SMT3 specific peptidase 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3b antibody, SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog antibody, SENP3 antibody, Senp3 antibody, senp3 antibody, senp3b antibody, senp3.L antibody

Background: SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.
Alias Symbols: DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3
Protein Interaction Partner: HIF1A, EP300, UBC, SUMO2, WDR5, ASH2L, KMT2D, RBBP5, KMT2A, MEN1, RNF2, HECW2, SOX2, LAS1L, PELP1, CDK6, CDK4, MOV10, CHCHD4, DHX15, ILF3, TRIM63, TRIM54, USP21, USP15, CDKN2A, RPS18, RPS11, RPS8, RPS4X, RPLP0, NPM1, PIDD1, NR1H2, TP53, MDM2, STUB1, HSP90
Protein Size: 574

Molecular Weight: 65 kDa

Gene ID: 26168

NCBI Accession: NM_015670, NP_056485

UniProt: Q9H4L4