HISPPD1 antibody (Middle Region)

Catalog No. ABIN2786093

Product Details anti-HISPPD1 Antibody

Target: HISPPD1 (PPIP5K2) (diphosphoinositol Pentakisphosphate Kinase 2 (PPIP5K2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Guinea Pig, Cow, Horse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HISPPD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HISPPD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HISPPD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HISPPD1

Target: HISPPD1 (PPIP5K2) (diphosphoinositol Pentakisphosphate Kinase 2 (PPIP5K2))

Alternative Name: HISPPD1 (PPIP5K2 Products)

Synonyms: HISPPD1 antibody, IP7K2 antibody, VIP2 antibody, AW555814 antibody, D330021B20 antibody, Hisppd1 antibody, Vip2 antibody, mKIAA0433 antibody, hisppd1 antibody, ip7k2 antibody, vip2 antibody, diphosphoinositol pentakisphosphate kinase 2 antibody, diphosphoinositol pentakisphosphate kinase 2 L homeolog antibody, PPIP5K2 antibody, Ppip5k2 antibody, ppip5k2.L antibody

Background: Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively.Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM].
Alias Symbols: FLJ21506, KIAA0433, PPIP5K2, VIP2, IP7K2, HISPPD1
Protein Interaction Partner: UBC, ZBTB8B, THOC7, ZC3H15, VAC14, WDR74, WDR6, SUMO1,
Protein Size: 1222

Molecular Weight: 138 kDa

Gene ID: 23262

NCBI Accession: NM_015216, NP_056031

UniProt: O43314

Pathways: Inositol Metabolic Process