KIFAP3 antibody (Middle Region)

Catalog No. ABIN2786068

Product Details anti-KIFAP3 Antibody

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIFAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KIFAP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 792 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Alternative Name: KIFAP3 (KIFAP3 Products)

Synonyms: CG11759 antibody, DmKAP antibody, DmKap antibody, Dmel\\CG11759 antibody, KAP antibody, KAP3 antibody, Kap antibody, dKAP3 antibody, kap3 antibody, FLA3 antibody, KAP-1 antibody, KAP-3 antibody, SMAP antibody, Smg-GDS antibody, dJ190I16.1 antibody, fb99h08 antibody, kifap3 antibody, wu:fb99h08 antibody, wz7228 antibody, Kinesin associated protein 3 antibody, kinesin-associated protein 3 antibody, kinesin associated protein 3 antibody, kinesin-associated protein 3b antibody, kinesin-associated protein 3 L homeolog antibody, Kap3 antibody, LOC551999 antibody, KIFAP3 antibody, Kifap3 antibody, kifap3b antibody, kifap3.L antibody

Background: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: NAA10, NCF2, UBC, PEX19, RBFOX1, KIF3A, VHL, RANBP2, MEST, DISC1, NIPSNAP3A, NUDT21, AR, RAP1GDS1, MINK1, SMC3, KIF3B, KIFAP3, MAP3K10, RPGR, SRC, APC, MAP3K11,
Protein Size: 792

Molecular Weight: 91 kDa

Gene ID: 22920

NCBI Accession: NM_014970, NP_055785

UniProt: Q92845

Pathways: Hedgehog Signaling, Sensory Perception of Sound