SAPS1 antibody (N-Term)

Catalog No. ABIN2786061

Product Details anti-SAPS1 Antibody

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAPS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MFWKFDLHTS SHLDTLLERE DLSLPELLDE EDVLQECKVV NRKLLDFLLQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SAPS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 881 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SAPS1

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Alternative Name: PPP6R1 (SAPS1 Products)

Synonyms: KIAA1115 antibody, PP6R1 antibody, SAP190 antibody, SAPS1 antibody, 2010309P17Rik antibody, AI836219 antibody, B430201G11Rik antibody, D030074N20Rik antibody, Pp6r1 antibody, Saps1 antibody, mKIAA1115 antibody, RGD1311409 antibody, pp6r1 antibody, MGC69001 antibody, protein phosphatase 6 regulatory subunit 1 antibody, protein phosphatase 6, regulatory subunit 1 antibody, protein phosphatase 6 regulatory subunit 1 L homeolog antibody, PPP6R1 antibody, Ppp6r1 antibody, ppp6r1.L antibody

Background: Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C, MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]).
Alias Symbols: KIAA1115, MGC138185, MGC142003, PP6R1, SAP190, SAPS1
Protein Interaction Partner: UBC, AGO1, ANKRD52, MOB1B, ANKRD44, ACAD11, SRPRB, PPP6R3, MOB1A, CNOT10, ANKRD28, CNOT1, ILVBL, PFDN6, C2CD5, KNTC1, PPP6R2, GTF3C4, ARHGEF2, USP10, SGPL1, IKBKAP, TTF2, SRPR, PPP6C, PFDN5, PFDN2, PDCD2, HSPA4, HADHB, HADHA, ACSL3, ALDH3A2, EGFR, HDAC11,
Protein Size: 881

Molecular Weight: 97 kDa

Gene ID: 22870

NCBI Accession: NM_014931, NP_055746

UniProt: Q9UPN7