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EDC4 antibody (N-Term)

EDC4 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786009
  • Target See all EDC4 Antibodies
    EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
    Binding Specificity
    • 15
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 29
    • 26
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
    Host
    • 37
    • 3
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EDC4 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4
    Top Product
    Discover our top product EDC4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1401 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Xu, Li, Li: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).

  • Target
    EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
    Alternative Name
    EDC4 (EDC4 Products)
    Synonyms
    VARICOSE antibody, ge-1 antibody, hedls antibody, rcd-8 antibody, GE1 antibody, Ge-1 antibody, HEDL5 antibody, HEDLS antibody, RCD-8 antibody, RCD8 antibody, BC022641 antibody, si:ch211-237c7.1 antibody, wu:fe26b05 antibody, LRRG00115 antibody, Nrn1l antibody, RGD1309136 antibody, enhancer of mRNA decapping 4 antibody, Transducin/WD40 repeat-like superfamily protein antibody, enhancer of mRNA decapping 4 L homeolog antibody, EDC4 antibody, VCS antibody, edc4 antibody, Edc4 antibody, edc4.L antibody
    Background
    In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
    Alias Symbols: Ge-1, HEDLS, RCD-8
    Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
    Protein Size: 1401
    Molecular Weight
    152 kDa
    Gene ID
    23644
    NCBI Accession
    NM_014329, NP_055144
    UniProt
    Q6P2E9
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