EDC4 antibody (N-Term)
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- Target See all EDC4 Antibodies
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EDC4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4
- Top Product
- Discover our top product EDC4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1401 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).
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Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).
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- Target
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
- Alternative Name
- EDC4 (EDC4 Products)
- Synonyms
- VARICOSE antibody, ge-1 antibody, hedls antibody, rcd-8 antibody, GE1 antibody, Ge-1 antibody, HEDL5 antibody, HEDLS antibody, RCD-8 antibody, RCD8 antibody, BC022641 antibody, si:ch211-237c7.1 antibody, wu:fe26b05 antibody, LRRG00115 antibody, Nrn1l antibody, RGD1309136 antibody, enhancer of mRNA decapping 4 antibody, Transducin/WD40 repeat-like superfamily protein antibody, enhancer of mRNA decapping 4 L homeolog antibody, EDC4 antibody, VCS antibody, edc4 antibody, Edc4 antibody, edc4.L antibody
- Background
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In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401 - Molecular Weight
- 152 kDa
- Gene ID
- 23644
- NCBI Accession
- NM_014329, NP_055144
- UniProt
- Q6P2E9
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