NOMO1 antibody (C-Term)

Catalog No. ABIN2785997

Product Details anti-NOMO1 Antibody

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOMO1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: QDIAQGSYIA LPLTLLVLLA GYNHDKLIPL LLQLTSRLQG VRALGQAASD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against NOMO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NOMO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOMO1

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Alternative Name: NOMO1 (NOMO1 Products)

Synonyms: Nomo antibody, PM5 antibody, D7Ertd156e antibody, pM5 antibody, RGD1305240 antibody, NOMO2 antibody, DKFZP459L1733 antibody, Nomo1 antibody, NODAL modulator 1 antibody, nodal modulator 1 antibody, NOMO1 antibody, Nomo1 antibody, LOC515570 antibody, LOC714226 antibody, LOC100025365 antibody, LOC100174326 antibody, LOC100408200 antibody, LOC100464689 antibody, LOC100544619 antibody, LOC100626015 antibody, LOC454345 antibody, LOC489992 antibody, LOC100713781 antibody

Background: NOMO1 was originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE).
Alias Symbols: Nomo, PM5, NOMO3
Protein Interaction Partner: UBC, TRIM63, TRIM55, EXOSC10, FBXO6, UPF2, STAT1, ECT2, TIMM10, PLEC, ILF3, UBQLN4, SHBG, CDK2, TOM1L1, BAG6, NCLN,
Protein Size: 1222

Molecular Weight: 134 kDa

Gene ID: 23420

NCBI Accession: NM_014287, NP_055102

UniProt: P69849