MRPL13 antibody (Middle Region)

Catalog No. ABIN2785985

Product Details anti-MRPL13 Antibody

Target: MRPL13 (Mitochondrial Ribosomal Protein L13 (MRPL13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Pig, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AIYGMLPKNL HRRTMMERLH LFPDEYIPED ILKNLVEELP QPRKIPKRLD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MRPL13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MRPL13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 178 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL13

Target: MRPL13 (Mitochondrial Ribosomal Protein L13 (MRPL13))

Alternative Name: MRPL13 (MRPL13 Products)

Synonyms: CG10602 antibody, CG10603 antibody, Dmel\\CG10603 antibody, L13 antibody, anon-EST:fe3C4 antibody, GB12738 antibody, MGC135435 antibody, zgc:109948 antibody, MRPL13 antibody, YK105 antibody, L13A antibody, L13mt antibody, RPL13 antibody, RPML13 antibody, 1110002D09Rik antibody, mitochondrial ribosomal protein L13 antibody, 39S ribosomal protein L13, mitochondrial antibody, mitochondrial ribosomal protein L13 S homeolog antibody, mitochondrial 54S ribosomal protein YmL13 antibody, Putative mitochondrial ribosomal protein L13 antibody, mRpL13 antibody, LOC413928 antibody, MRPL13 antibody, mrpl13.S antibody, mrpl13 antibody, LOC770396 antibody, mrpL13 antibody, Mrpl13 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Alias Symbols: L13, L13mt, RPL13, RPML13, L13A
Protein Interaction Partner: FN1, MRPL55, MRPL10, MRPL52, MRPL45, MRPL24, MRPL44, MRPL9, MRPL11, MRPL38, MRPL41, MRPS9, MRPL14, MRPL17, MRPL16, MRPL39, MRPL2, MRPL15, MRPL42, MRPS28, SCFD1, MRPL3, CUL7, MRPL19, MRPL23, SLC25A3, OGDH, NDUFS1, NDUFB10, MPV17, ICT1, HNRNPU, DLD, UBC, OX
Protein Size: 178

Molecular Weight: 21 kDa

Gene ID: 28998

NCBI Accession: NM_014078, NP_054797

UniProt: Q9BYD1