IARS antibody (N-Term)

Catalog No. ABIN2785973

Product Details anti-IARS Antibody

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKHKPKFTFY DGPPFATGLP HYGHILAGTI KDIVTRYAHQ SGFHVDRRFG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%, Yeast: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against IARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IARS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1262 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IARS

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Alternative Name: IARS (IARS Products)

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first prot
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: UBC, MDM2, SART3, AURKA, SUMO2, SUMO3, STAU1, LGR4, AIMP2, RPLP0, RPL38, RPL24, RPL23A, RPL18, RPL15, QARS, NMT1, MARS, MAP4, HNRNPA2B1, EPRS, DARS, AIMP1, HNRNPUL2, LARS, RPS27L, IGF2BP3, SYNCRIP, EEF1E1, FBXO6, EGFR, UBD, ITGA4, FN1, METTL18, gag, VCAM1
Protein Size: 1262

Molecular Weight: 144 kDa

Gene ID: 3376

NCBI Accession: XM_001126273, NP_038203

UniProt: P41252