TIMM13 antibody (N-Term)

Catalog No. ABIN2785946

Product Details anti-TIMM13 Antibody

Target: TIMM13 (Translocase of Inner Mitochondrial Membrane 13 Homolog (TIMM13))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FGSDFGGTGG GKLDPGAIME QVKVQIAVAN AQELLQRMTD KCFRKCIGKP

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Timm13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 95 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TIMM13

Target: TIMM13 (Translocase of Inner Mitochondrial Membrane 13 Homolog (TIMM13))

Alternative Name: Timm13 (TIMM13 Products)

Synonyms: TIM13 antibody, TIM13B antibody, TIMM13A antibody, TIMM13B antibody, ppv1 antibody, D10Ertd378e antibody, Tim9 antibody, Timm9 antibody, fd44h11 antibody, zgc:92895 antibody, wu:fd44h11 antibody, TIMM13 antibody, T25B24.8 antibody, T25B24_8 antibody, translocase of the inner mitochondrial membrane 13 antibody, CaO19.2754 antibody, tim13 antibody, tim13b antibody, timm13 antibody, timm13-a antibody, timm13-b antibody, timm13a antibody, timm13b antibody, translocase of inner mitochondrial membrane 13 antibody, translocase of inner mitochondrial membrane 13 homolog (yeast) antibody, translocase of the inner mitochondrial membrane 13 antibody, protein translocase subunit antibody, translocase of inner mitochondrial membrane 13 homolog L homeolog antibody, translocase of inner mitochondrial membrane 13 homolog S homeolog antibody, TIMM13 antibody, Timm13 antibody, timm13 antibody, TIM13 antibody, timm13.L antibody, timm13.S antibody

Background: Timm13 is a mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. It acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Alias Symbols: D10Ertd378e, Tim9, Timm9
Protein Size: 95

Molecular Weight: 10 kDa

Gene ID: 30055

NCBI Accession: NM_013895, NP_038923

UniProt: P62075

Pathways: Sensory Perception of Sound