MTO1 antibody (N-Term)

Catalog No. ABIN2785915

Product Details anti-MTO1 Antibody

Target: MTO1

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: STVYAESVIL TTGTFLRGMI VIGLETHPAG RLGDQPSIGL AQTLEKLGFV

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MTO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MTO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 732 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTO1

Target: MTO1

Abstract: MTO1 Products

Synonyms: 2310039H01Rik antibody, 5730419A02Rik antibody, COXPD10 antibody, mitochondrial tRNA translation optimization 1 antibody, Mto1 antibody, MTO1 antibody

Background: MTO1 is a mitochondrial protein thought to be involved in mitochondrial tRNA modification. It may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene.This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CGI-02
Protein Interaction Partner: UBC, KDM1A, SUV39H1,
Protein Size: 732

Molecular Weight: 81 kDa

Gene ID: 25821

NCBI Accession: NM_001123226, NP_001116698

UniProt: Q9Y2Z2