LASP1 antibody (Middle Region)

Catalog No. ABIN2785890

Product Details anti-LASP1 Antibody

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IKKTQDQISN IKYHEEFEKS RMGPSGGEGM EPERRDSQDG SSYRRPLEQQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LASP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LASP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 261 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LASP1 antibody (ABIN2785890)

Stone, Merriman, Cantor, Geschwind, Nelson: "High density SNP association study of a major autism linkage region on chromosome 17." in: Human molecular genetics, Vol. 16, Issue 6, pp. 704-15, (2007) (PubMed).

Target Details for LASP1

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Alternative Name: LASP1 (LASP1 Products)

Synonyms: lasp1 antibody, MGC53336 antibody, LASP1 antibody, MGC89667 antibody, Lasp-1 antibody, MLN50 antibody, AA408629 antibody, Def-4 antibody, SH3P6 antibody, Tg(Col1a1-lacZ)1Ngma antibody, fb92f05 antibody, wu:fb92f05 antibody, zgc:77542 antibody, lasp-1 antibody, mln50 antibody, LIM and SH3 protein 1 antibody, LIM and SH3 protein 1 L homeolog antibody, lasp1 antibody, lasp1.L antibody, LASP1 antibody, Lasp1 antibody

Background: LASP1 is a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. It functions as an actin-binding protein and possibly in cytoskeletal organization.This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Lasp-1, MLN50
Protein Interaction Partner: ZBTB9, KRTAP4-2, RHOXF2, LZTS2, SEPT3, THAP1, ZC2HC1A, ARHGEF15, SPRY2, FXR2, TRIP13, TCF4, TRIM27, REL, PSMA3, GOLGA2, SUMO2, UBC, MDFI, CD81, Prkg1, Prkaca, DAZAP2, ATXN1, FN1, ACD, TINF2, POT1, TERF1, Fancc, CDK7, FHL3, PRKG2, PLSCR1, ZYX, PRKAR2B, ACT
Protein Size: 261

Molecular Weight: 30 kDa

Gene ID: 3927

NCBI Accession: NM_006148, NP_006139

UniProt: Q14847