HADH antibody (C-Term)

Catalog No. ABIN2785872

Product Details anti-HADH Antibody

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HADH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YPMGPFELLD YVGLDTTKFI VDGWHEMDAE NPLHQPSPSL NKLVAENKFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HADH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HADH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HADH

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Alternative Name: HADH (HADH Products)

Synonyms: HAD antibody, HADHSC antibody, hadhsc antibody, wu:fb66a11 antibody, zgc:86777 antibody, Hadhsc antibody, HADH1 antibody, HCDH antibody, HHF4 antibody, MSCHAD antibody, SCHAD antibody, AA409008 antibody, AU019341 antibody, AW742602 antibody, Schad antibody, hydroxyacyl-CoA dehydrogenase antibody, hydroxyacyl-CoA dehydrogenase L homeolog antibody, hydroxyacyl-Coenzyme A dehydrogenase antibody, 3-hydroxyacyl-CoA dehydrogenase (short-chain) antibody, Short chain 3-hydroxyacyl-CoA dehydrogenase antibody, short chain 3-hydroxyacyl-coa dehydrogenase antibody, putative short chain 3-hydroxyacyl-CoA dehydrogenase antibody, HADH antibody, hadh antibody, hadh.L antibody, Hadh antibody, CNI02410 antibody, Tc00.1047053509717.90 antibody, Tc00.1047053510105.240 antibody, LMJF_36_1140 antibody

Background: HADH functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HAD, HADH1, HADHSC, HHF4, M/SCHAD, MGC8392, SCHAD, HCDH, MSCHAD
Protein Interaction Partner: MDM2, STAT1, ADH1A, APP, UBC, MAPK3, UBA5, HADH, SLC2A4,
Protein Size: 314

Molecular Weight: 33 kDa

Gene ID: 3033

NCBI Accession: NM_005327, NP_005318

UniProt: Q16836

Pathways: Negative Regulation of Hormone Secretion, Monocarboxylic Acid Catabolic Process