Fibromodulin antibody (N-Term)

Catalog No. ABIN2785800

Product Details anti-Fibromodulin Antibody

Target: Fibromodulin (FMOD)

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VYFQNNQITS IQEGVFDNAT GLLWIALHGN QITSDKVGRK VFSKLRHLER

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMOD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMOD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD (FMOD Products)

Synonyms: FMOD antibody, AI131919 antibody, AU041740 antibody, SLRR2E antibody, LOC100286414 antibody, sc:d0415 antibody, si:dkey-31j12.4 antibody, LOC100229381 antibody, FM antibody, fibromodulin antibody, fibromodulin b antibody, FMOD antibody, Fmod antibody, LOC100286414 antibody, fmodb antibody

Background: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SLRR2E
Protein Interaction Partner: BTBD1, ZBTB32, CUL3, Dlg4, TGFB3, TGFB2, TGFB1,
Protein Size: 376

Molecular Weight: 43 kDa

Gene ID: 2331

NCBI Accession: NM_002023, NP_002014

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process