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ARF6 antibody (Middle Region)

ARF6 Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Sheep, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785790
  • Target See all ARF6 Antibodies
    ARF6 (ADP-Ribosylation Factor 6 (ARF6))
    Binding Specificity
    • 15
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 57
    • 25
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Sheep, Dog
    Host
    • 56
    • 1
    Rabbit
    Clonality
    • 48
    • 9
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARF6 antibody is un-conjugated
    Application
    • 19
    • 13
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    REMRDAIILI FANKQDLPDA MKPHEIQEKL GLTRIRDRNW YVQPSCATSG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ARF6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ARF6
    Top Product
    Discover our top product ARF6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 175 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tagliatti, Fadda, Falace, Benfenati, Fassio: "Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse." in: eLife, Vol. 5, (2016) (PubMed).

  • Target
    ARF6 (ADP-Ribosylation Factor 6 (ARF6))
    Alternative Name
    ARF6 (ARF6 Products)
    Synonyms
    AI788669 antibody, AW496366 antibody, MGC80156 antibody, arf6 antibody, wu:fj46d09 antibody, zgc:77665 antibody, wu:fa98a01 antibody, zgc:172028 antibody, ADP ribosylation factor 6 antibody, ADP-ribosylation factor 6 antibody, ADP ribosylation factor 6 L homeolog antibody, Arf6 protein antibody, ADP-ribosylation factor 6a antibody, ADP-ribosylation factor 6b antibody, ADP ribosylation factor like GTPase 6 antibody, ARF6 antibody, Arf6 antibody, arf6.2.L antibody, arf6 antibody, arf6a antibody, arf6b antibody, ARL6 antibody
    Background
    ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DKFZp564M0264
    Protein Interaction Partner: UBC, LSB5, GGA1, STAU1, EGFR, CYTH1, CYTH2, GNAQ, FN1, VCP, APP, RAB11FIP3, RAB11FIP4, RAB11FIP5, USP6, IKBKG, GGA3, ITSN1, ASAP1, FBXO8, MEPCE, RUVBL2, ASAP3, MPP5, ZNF709, EXOC5, ARFIP2, AP3D1, PIP5K1C, ASAP2, AP3B1, PIP5K1A, PLD1, AP1B1, EZR, CHRM3, CA
    Protein Size: 175
    Molecular Weight
    20 kDa
    Gene ID
    382
    NCBI Accession
    NM_001663, NP_001654
    UniProt
    P62330
    Pathways
    Steroid Hormone Mediated Signaling Pathway, Regulation of Actin Filament Polymerization, SARS-CoV-2 Protein Interactome
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