ACADVL antibody (N-Term)

Catalog No. ABIN2785735

Product Details anti-ACADVL Antibody

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADVL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RPYAGGAAQE SKSFAVGMFK GQLTTDQVFP YPSVLNEEQT QFLKELVEPV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ACADVL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACADVL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 633 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACADVL antibody (ABIN2785735)

Yoon, Kang, Ryu, Poo: "Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress." in: Cell proliferation, Vol. 43, Issue 6, pp. 584-93, (2010) (PubMed).

Target Details for ACADVL

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Alternative Name: ACADVL (ACADVL Products)

Synonyms: ACAD6 antibody, LCACD antibody, VLCAD antibody, vlcad antibody, fb52d04 antibody, wu:fb52d04 antibody, wu:fc75e01 antibody, zgc:64067 antibody, acyl-CoA dehydrogenase very long chain antibody, acyl-Coenzyme A dehydrogenase, very long chain antibody, acyl-CoA dehydrogenase, very long chain antibody, ACADVL antibody, Acadvl antibody, acadvl antibody

Background: ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in ACADVL protein reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ACAD6, LCACD, VLCAD
Protein Interaction Partner: EEF2K, GPHN, RPSA, ATF2, CDH1, INTS9, ATP5L, UBC, SOCS3, ICT1, ACADVL,
Protein Size: 633

Molecular Weight: 64 kDa

Gene ID: 37

NCBI Accession: NM_001033859, NP_001029031

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process