NLRP1 antibody (N-Term)

Catalog No. ABIN2785731

Product Details anti-NLRP1 Antibody

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DTQEPRIVIL QGAAGIGKST LARQVKEAWG RGQLYGDRFQ HVFYFSCREL

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NLRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1375 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Alternative Name: NLRP1 (NLRP1 Products)

Synonyms: CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody

Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like
Alias Symbols: CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1
Protein Interaction Partner: TRIM68, CUL3, APOA1, NLRP1, PYCARD, NOD1, CASP5, CASP9, APAF1, CASP2, BCL2L1, BCL2, CASP1, NLRC4,
Protein Size: 1375

Molecular Weight: 155 kDa

Gene ID: 22861

NCBI Accession: NM_001033053, NP_001028225

UniProt: Q9C000

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome