IMPDH1 antibody (Middle Region)
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- Target See all IMPDH1 Antibodies
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IMPDH1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KKGKLPIVND CDELVAIIAR TDLKKNRDYP LASKDSQKQL LCGAAVGTRE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1
- Top Product
- Discover our top product IMPDH1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 563 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
- Alternative Name
- IMPDH1 (IMPDH1 Products)
- Synonyms
- IMPD antibody, IMPD1 antibody, LCA11 antibody, RP10 antibody, sWSS2608 antibody, B930086D20Rik antibody, IMPD 1 antibody, IMPDH 1 antibody, D3 antibody, IMPD 1b antibody, IMPDH 1b antibody, IMPDH1 antibody, id:ibd5035 antibody, si:dkey-31f5.7 antibody, wu:fa09h11 antibody, wu:fa99c03 antibody, zgc:113446 antibody, imp antibody, imp1 antibody, imp2 antibody, IMPD 1a antibody, IMPDH 1a antibody, zgc:91911 antibody, inosine monophosphate dehydrogenase 1 antibody, inosine-5'-monophosphate dehydrogenase 1 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1b antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1a antibody, IMPDH1 antibody, Impdh1 antibody, LOC100442769 antibody, impdh1 antibody, impdh1b antibody, impdh1.L antibody, impdh1a antibody
- Background
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IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Alias Symbols: DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Protein Interaction Partner: UBC, LAMP2, IMPDH2, XRCC6, GMNN, HTRA1, DDX3X, SUMO4,
Protein Size: 563 - Molecular Weight
- 62 kDa
- Gene ID
- 3614
- NCBI Accession
- NM_183243, NP_899066
- UniProt
- P20839
- Pathways
- Ribonucleoside Biosynthetic Process
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