SQSTM1 antibody (Middle Region)
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- Target See all SQSTM1 Antibodies
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Sheep, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SQSTM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EEQMESDNCS GGDDDWTHLS SKEVDPSTGE LQSLQMPESE GPSSLDPSQE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against SQSTM1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1
- Top Product
- Discover our top product SQSTM1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 440 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Alternative Name
- SQSTM1 (SQSTM1 Products)
- Synonyms
- SQSTM1 antibody, sqstm1 antibody, MGC79491 antibody, A170 antibody, OSIL antibody, PDB3 antibody, ZIP3 antibody, p60 antibody, p62 antibody, p62B antibody, OSF-6 antibody, Osi antibody, STAP antibody, ZIP antibody, sb:cb621 antibody, zgc:85784 antibody, sequestosome 1 antibody, sequestosome 1 L homeolog antibody, SQSTM1 antibody, sqstm1 antibody, Sqstm1 antibody, sqstm1.L antibody
- Background
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This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to m
Alias Symbols: A170, OSIL, PDB3, ZIP3, p60, p62, p62B
Protein Interaction Partner: HTT, BCL2, ATXN3, MAP1LC3A, tat, GABARAPL1, GABARAPL2, KEAP1, SQSTM1, UBC, TP53, TRIM63, TRIM55, MAP1LC3B, TOLLIP, ULK1, GABARAP, OPTN, SESN2, SUMO3, NBR1, EPAS1, EGLN3, CFTR, DCP2, MGRN1, NEDD8, EDEM1, LGALS3, IKBKG, TNK2, DVL2, FLNB, PSMD12, PSMD10, PSM
Protein Size: 440 - Molecular Weight
- 48 kDa
- Gene ID
- 8878
- NCBI Accession
- NM_003900, NP_003891
- UniProt
- Q13501
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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