SPAG11B antibody (N-Term)

Catalog No. ABIN2785534

Product Details anti-SPAG11B Antibody

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG11B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MRQRLLPSVT SLLLVALLFP GSSQARHVNH SATEALGELR ERAPGQGTNG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SPAG11B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPAG11B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 133 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPAG11B

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Alternative Name: SPAG11B (SPAG11B Products)

Synonyms: EDDM2B antibody, EP2 antibody, EP2C antibody, EP2D antibody, HE2 antibody, HE2C antibody, SPAG11 antibody, Bin1b antibody, Spag11 antibody, Ep2c/h antibody, EG546038 antibody, Spag11c/h antibody, SPAG11B antibody, 9230111C08Rik antibody, EP2Q antibody, EP2e antibody, sperm associated antigen 11B antibody, sperm associated antigen 11A antibody, SPAG11B antibody, Spag11a antibody, Spag11b antibody

Background: SPAG11B is one of several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides.This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined.
Alias Symbols: EP2, EP2C, EP2D, HE2, HE2C, MGC61846, SPAG11, EDDM2B
Protein Size: 133

Molecular Weight: 15 kDa

Gene ID: 10407

NCBI Accession: NM_058201, NP_478108