OAZ3 antibody (Middle Region)

Catalog No. ABIN2785531

Product Details anti-OAZ3 Antibody

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DRRLFLDIPY QALDQGNRES LTATLEYVEE KTNVDSVFVN FQNDRNDRGA

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against OAZ3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OAZ3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 187 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OAZ3

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Alternative Name: OAZ3 (OAZ3 Products)

Synonyms: Az3 antibody, Oaz-t antibody, AZ3 antibody, OAZ-t antibody, TISP15 antibody, Az-3 antibody, ornithine decarboxylase antizyme 3 antibody, OAZ3 antibody, Oaz3 antibody

Background: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AZ3, OAZ-t, TISP15
Protein Interaction Partner: AZIN2, C1orf94, L3MBTL3, AZIN1, IKZF3, BLZF1, REL, ODC1, OAZ1, GGN, SMAD1,
Protein Size: 187

Molecular Weight: 21 kDa

Gene ID: 51686

NCBI Accession: NM_016178, NP_057262

UniProt: Q9UMX2