PDHA2 antibody (N-Term)

Catalog No. ABIN2785491

Product Details anti-PDHA2 Antibody

Target: PDHA2 (PDHa2) (Pyruvate Dehydrogenase (Lipoamide) alpha 2 (PDHa2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDHA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RMELKADQLY KQKFIRGFCH LCDGQEACCV GLEAGINPSD HVITSYRAHG

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PDHA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDHA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDHA2

Target: PDHA2 (PDHa2) (Pyruvate Dehydrogenase (Lipoamide) alpha 2 (PDHa2))

Alternative Name: PDHA2 (PDHa2 Products)

Background: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Alias Symbols: MGC149517, MGC149518, PDHAL
Protein Interaction Partner: MSMO1, HNRNPU, DLAT, CAND1, COPS5, CUL3, PDHB,
Protein Size: 388

Molecular Weight: 43 kDa

Gene ID: 5161

NCBI Accession: NM_005390, NP_005381

UniProt: P29803

Pathways: Warburg Effect