CRISP1 antibody (N-Term)
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- Target See all CRISP1 Antibodies
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Cow, Goat, Pig, Rabbit, Zebrafish (Danio rerio), Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRISP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LKMSWSEEAA QNARIFSKYC DMTESNPLER RLPNTFCGEN MHMTSYPVSW
- Predicted Reactivity
- Cow: 85%, Dog: 85%, Goat: 85%, Human: 100%, Pig: 85%, Rabbit: 79%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CRISP1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CRISP1
- Top Product
- Discover our top product CRISP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 249 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
- Alternative Name
- CRISP1 (CRISP1 Products)
- Synonyms
- AEGL1 antibody, ARP antibody, CRISP-1 antibody, HSCRISP1D antibody, HSCRISP1G antibody, HUMARP antibody, AW324342 antibody, Aeg1 antibody, AEG antibody, crisp-1 antibody, cysteine rich secretory protein 1 antibody, cysteine-rich secretory protein 1 antibody, CRISP1 antibody, Crisp1 antibody
- Background
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Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene.
Alias Symbols: AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Protein Size: 249 - Molecular Weight
- 27 kDa
- Gene ID
- 167
- NCBI Accession
- NM_001131, NP_001122
- UniProt
- P54107
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