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DNAJC24 antibody (N-Term)

DNAJC24 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785377
  • Target See all DNAJC24 Antibodies
    DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))
    Binding Specificity
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This DNAJC24 antibody is un-conjugated
    Application
    • 20
    • 15
    • 1
    Western Blotting (WB)
    Sequence
    MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG
    Predicted Reactivity
    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against DPH4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DPH4
    Top Product
    Discover our top product DNAJC24 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 149 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))
    Alternative Name
    DPH4 (DNAJC24 Products)
    Synonyms
    DPH4 antibody, JJJ3 antibody, ZCSL3 antibody, 1700030A21Rik antibody, 2610027M02Rik antibody, AV066965 antibody, AW240712 antibody, Dph4 antibody, MmDjC7 antibody, Zcsl3 antibody, RGD1564710 antibody, DnaJ heat shock protein family (Hsp40) member C24 antibody, DNAJC24 antibody, Dnajc24 antibody
    Background
    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2.Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 CD685768.1 19-28 11-652 AL833128.1 1-642 653-3000 AC108456.7 42515-44862
    Alias Symbols: JJJ3, ZCSL3, DPH4
    Protein Size: 149
    Molecular Weight
    17 kDa
    Gene ID
    120526
    NCBI Accession
    NM_181706, NP_859057
    UniProt
    Q6P3W2
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