SH2D3C antibody (N-Term)

Catalog No. ABIN2785290

Product Details anti-SH2D3C Antibody

Target: SH2D3C (SH2 Domain Containing 3C (SH2D3C))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D3C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGSDYVKFSK EKYILDSSPE KLHKELEEEL KLSSTDLRSH AWYHGRIPRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SH2D3C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SH2D3C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH2D3C

Target: SH2D3C (SH2 Domain Containing 3C (SH2D3C))

Alternative Name: SH2D3C (SH2D3C Products)

Synonyms: sh2d3c antibody, zgc:56490 antibody, SH2D3C antibody, CHAT antibody, NSP3 antibody, PRO34088 antibody, SHEP1 antibody, Chat antibody, Nsp3 antibody, Shep1 antibody, SH2 domain containing 3Cb antibody, SH2 domain containing 3C antibody, SH2 domain-containing protein 3C antibody, SH2 domain containing 3C L homeolog antibody, sh2d3cb antibody, SH2D3C antibody, LOC100466471 antibody, sh2d3c antibody, sh2d3c.L antibody, Sh2d3c antibody

Background: SH2D3C is an Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 of SH2D3C is required to induce membrane ruffling and promote EGF-dependent cell migration.
Alias Symbols: CHAT, FLJ39664, NSP3, PRO34088
Protein Interaction Partner: LYN, NEDD9, EFS, CARD11, SNCAIP, BCAR1, PTK2B, EPHB2, SRC, MAPK1,
Protein Size: 703

Molecular Weight: 77 kDa

Gene ID: 10044

NCBI Accession: NM_170600, NP_733745