FBXO39 antibody (N-Term)

Catalog No. ABIN2785254

Product Details anti-FBXO39 Antibody

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rabbit, Dog, Guinea Pig, Rat, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO39 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DRSRAALVCR KWNQMMYSAE LWRYRTITFS GRPSRVHASE VESAVWYVKK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO39

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO39

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Alternative Name: FBXO39 (FBXO39 Products)

Synonyms: Fbx39 antibody, 1700010H23Rik antibody, F-box protein 39 antibody, FBXO39 antibody, Fbxo39 antibody

Background: FBXO39 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO39, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx39, MGC35179
Protein Size: 442

Molecular Weight: 53 kDa

Gene ID: 162517

NCBI Accession: NM_153230, NP_694962

UniProt: Q8N4B4