OMA1 antibody (Middle Region)

Catalog No. ABIN2785108

Product Details anti-OMA1 Antibody

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Cow, Rabbit, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WAICPRDSLA LLCQWIQSKL QEYMFNRPYS RKLEAEADKI GLLLAAKACA

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Yeast: 83%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against OMA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OMA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-OMA1 antibody (ABIN2785108)

Bohovych, Fernandez, Rahn, Stackley, Bestman, Anandhan, Franco, Claypool, Lewis, Chan, Khalimonchuk: "Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability." in: Scientific reports, Vol. 5, pp. 13989, (2015) (PubMed).

Bohovych, Donaldson, Christianson, Zahayko, Khalimonchuk: "Stress-triggered activation of the metalloprotease Oma1 involves its C-terminal region and is important for mitochondrial stress protection in yeast." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13259-72, (2014) (PubMed).

Target Details for OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Alternative Name: OMA1 (OMA1 Products)

Synonyms: 2010001O09Rik antibody, DAB1 antibody, MPRP-1 antibody, YKR087C antibody, ZMPOMA1 antibody, peptidase antibody, RGD1304821 antibody, oma1 antibody, OMA1 zinc metallopeptidase antibody, si:ch73-215a11.1 antibody, olfactory receptor 4K2 antibody, OMA1 antibody, Oma1 antibody, si:ch73-215a11.1 antibody, LOC531304 antibody

Background: OMA1 is a mitochondrial protease.
Alias Symbols: 2010001O09Rik, DAB1, FLJ33782, MPRP-1, YKR087C, ZMPOMA1
Protein Size: 524

Molecular Weight: 60 kDa

Gene ID: 115209

NCBI Accession: NM_145243, NP_660286

UniProt: Q96E52