ABRA antibody (Middle Region)

Catalog No. ABIN2785041

Product Details anti-ABRA Antibody

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABRA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QWADEHIQSQ KLNPFSEEFD YELAMSTRLH KGDEGYGRPK EGTKTAERAK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ABRA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABRA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABRA

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Alternative Name: ABRA (ABRA Products)

Synonyms: STARS antibody, C130068O12Rik antibody, Ms1 antibody, Stars antibody, actin binding Rho activating protein antibody, actin-binding Rho activating protein antibody, ABRA antibody, Abra antibody

Background: ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
Alias Symbols: STARS
Protein Interaction Partner: ABLIM2, ABLIM3, ABLIM1, ACTA1, ACTB, ACTC1,
Protein Size: 381

Molecular Weight: 43 kDa

Gene ID: 137735

NCBI Accession: NM_139166, NP_631905

UniProt: Q8N0Z2

Pathways: Protein targeting to Nucleus