DYX1C1 antibody (Middle Region)

Catalog No. ABIN2784980

Product Details anti-DYX1C1 Antibody

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYX1C1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TDNANARMKA HVRRGTAFCQ LELYVEGLQD YEAALKIDPS NKIVQIDAEK

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DYX1C1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DYX1C1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 420 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYX1C1

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Alternative Name: DYX1C1 (DYX1C1 Products)

Synonyms: DYX1 antibody, DYXC1 antibody, EKN1 antibody, RD antibody, 1700010I24Rik antibody, Edem2 antibody, Ekn1 antibody, zgc:77853 antibody, LOC100220614 antibody, dynein axonemal assembly factor 4 antibody, dyslexia susceptibility 1 candidate 1 antibody, dynein axonemal assembly factor 4 L homeolog antibody, DNAAF4 antibody, Dyx1c1 antibody, Dnaaf4 antibody, dnaaf4 antibody, DYX1C1 antibody, dnaaf4.L antibody

Background: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
Alias Symbols: DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD
Protein Interaction Partner: SPDL1, KDM1A, Stub1, Hspa1b, GABARAPL1, GABARAP, HSPA1A,
Protein Size: 420

Molecular Weight: 48 kDa

Gene ID: 161582

NCBI Accession: NM_130810, NP_570722

UniProt: Q8WXU2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling