KLHDC3 antibody (N-Term)

Catalog No. ABIN2784950

Product Details anti-KLHDC3 Antibody

Target: KLHDC3 (Kelch Domain Containing 3 (KLHDC3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHDC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLRWTVHLEG GPRRVNHAAV AVGHRVYSFG GYCSGEDYET LRQIDVHIFN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against KLHDC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLHDC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLHDC3

Target: KLHDC3 (Kelch Domain Containing 3 (KLHDC3))

Alternative Name: KLHDC3 (KLHDC3 Products)

Synonyms: klhdc3 antibody, MGC69171 antibody, KLHDC3 antibody, PEAS antibody, RP1-20C7.3 antibody, dJ20C7.3 antibody, 1300011D16Rik antibody, Peas antibody, kelch domain containing 3 L homeolog antibody, kelch domain containing 3 antibody, klhdc3.L antibody, KLHDC3 antibody, klhdc3 antibody, Klhdc3 antibody

Background: The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination.
Alias Symbols: PEAS, RP1-20C7.3, dJ20C7.3, hPEAS
Protein Interaction Partner: CSNK1E, CUL2, CUL5, TCEB2, TCEB1, UBC, UBXN7, DLG3,
Protein Size: 382

Molecular Weight: 43 kDa

Gene ID: 116138

NCBI Accession: NM_057161, NP_476502

UniProt: Q9BQ90

Pathways: Chromatin Binding, ER-Nucleus Signaling