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COPB1 antibody (Middle Region)

COPB1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784899
  • Target See all COPB1 Antibodies
    COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 50
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
    Host
    • 50
    • 1
    Rabbit
    Clonality
    • 50
    • 1
    Polyclonal
    Conjugate
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPB1 antibody is un-conjugated
    Application
    • 24
    • 23
    • 13
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    QLALDLVSSR NVEELVIVLK KEVIKTNNVS EHEDTDKYRQ LLVRTLHSCS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against COPB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human COPB1
    Top Product
    Discover our top product COPB1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 953 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Goryachev, Pokhilko: "Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).

  • Target
    COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
    Alternative Name
    COPB1 (COPB1 Products)
    Synonyms
    id:ibd5034 antibody, wu:fc66c05 antibody, zgc:92482 antibody, COPB1 antibody, DKFZp459K154 antibody, COPB antibody, 2610019B04Rik antibody, Rack2 antibody, Beta-COP antibody, coatomer protein complex, subunit beta 1 antibody, coatomer protein complex subunit beta 1 L homeolog antibody, coatomer protein complex subunit beta 1 antibody, copb1 antibody, copb1.L antibody, COPB1 antibody, Copb1 antibody
    Background
    The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
    Alias Symbols: COPB, DKFZp761K102, FLJ10341
    Protein Interaction Partner: SUMO2, NUDCD1, UBC, RNF2, EZH2, KLC1, DIAPH1, ARCN1, ACACA, COPG1, COPZ1, TLE3, FBXO6, UBD, KCNK3, KCNK9, NPM1, HDAC10, ERBB2IP, SNTA1, LZTS2, VPS18, NUB1, SERTAD1, FOXB1, IRAK3, TANK, ID1, HLA-DPB1, GRB2, XRCC6, FN1, CFTR, FMNL1, COPG2, COPE, COPB2, COPA
    Protein Size: 953
    Molecular Weight
    107 kDa
    Gene ID
    1315
    NCBI Accession
    NM_016451, NP_057535
    UniProt
    P53618
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