COPB1 antibody (Middle Region)
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- Target See all COPB1 Antibodies
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COPB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QLALDLVSSR NVEELVIVLK KEVIKTNNVS EHEDTDKYRQ LLVRTLHSCS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against COPB1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human COPB1
- Top Product
- Discover our top product COPB1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 953 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).
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Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).
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- Target
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
- Alternative Name
- COPB1 (COPB1 Products)
- Synonyms
- id:ibd5034 antibody, wu:fc66c05 antibody, zgc:92482 antibody, COPB1 antibody, DKFZp459K154 antibody, COPB antibody, 2610019B04Rik antibody, Rack2 antibody, Beta-COP antibody, coatomer protein complex, subunit beta 1 antibody, coatomer protein complex subunit beta 1 L homeolog antibody, coatomer protein complex subunit beta 1 antibody, copb1 antibody, copb1.L antibody, COPB1 antibody, Copb1 antibody
- Background
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The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPB, DKFZp761K102, FLJ10341
Protein Interaction Partner: SUMO2, NUDCD1, UBC, RNF2, EZH2, KLC1, DIAPH1, ARCN1, ACACA, COPG1, COPZ1, TLE3, FBXO6, UBD, KCNK3, KCNK9, NPM1, HDAC10, ERBB2IP, SNTA1, LZTS2, VPS18, NUB1, SERTAD1, FOXB1, IRAK3, TANK, ID1, HLA-DPB1, GRB2, XRCC6, FN1, CFTR, FMNL1, COPG2, COPE, COPB2, COPA
Protein Size: 953 - Molecular Weight
- 107 kDa
- Gene ID
- 1315
- NCBI Accession
- NM_016451, NP_057535
- UniProt
- P53618
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