FGL2 antibody (Middle Region)

Catalog No. ABIN2784837

Product Details anti-FGL2 Antibody

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FGL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 439 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FGL2 antibody (ABIN2784837)

Pischke, Gustavsen, Orrem, Egge, Courivaud, Fontenelle, Despont, Bongoni, Rieben, Tønnessen, Nunn, Scott, Skulstad, Barratt-Due, Mollnes: "Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function." in: Basic research in cardiology, Vol. 112, Issue 3, pp. 20, (2017) (PubMed).

Bongoni, Klymiuk, Wolf, Ayares, Rieben, Cowan: "Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation." in: Transplantation, Vol. 100, Issue 9, pp. 1871-9, (2016) (PubMed).

Target Details for FGL2

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Alternative Name: FGL2 (FGL2 Products)

Synonyms: FGL2 antibody, wu:fj83c10 antibody, zgc:136619 antibody, si:ch211-276e22.3 antibody, fibroleukin antibody, T49 antibody, pT49 antibody, AI385601 antibody, musfiblp antibody, fibrinogen like 2 antibody, fibrinogen like 2 L homeolog antibody, fibrinogen-like 2a antibody, fibrinogen-like 2 antibody, fibrinogen-like protein 2 antibody, FGL2 antibody, fgl2.L antibody, fgl2a antibody, Fgl2 antibody

Background: The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
Alias Symbols: T49, pT49
Protein Size: 439

Molecular Weight: 48 kDa

Gene ID: 10875

NCBI Accession: NM_006682, NP_006673

UniProt: Q14314