CPLX2 antibody (N-Term)

Catalog No. ABIN2784835

Product Details anti-CPLX2 Antibody

Target: CPLX2 (Complexin 2 (CPLX2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPLX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDFVMKQALG GATKDMGKML GGEEEKDPDA QKKEEERQEA LRQQEEERKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CPLX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPLX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 134 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPLX2

Target: CPLX2 (Complexin 2 (CPLX2))

Alternative Name: CPLX2 (CPLX2 Products)

Synonyms: 921-L antibody, CPX-2 antibody, CPX2 antibody, Hfb1 antibody, AI413745 antibody, AW492120 antibody, MGC68923 antibody, MGC79539 antibody, complexin 2 antibody, complexin 2 L homeolog antibody, complexin-2 antibody, CPLX2 antibody, Cplx2 antibody, cplx2.L antibody, cplx2 antibody, LOC750228 antibody

Background: Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: 921-L, CPX-2, CPX2, Hfb1, MGC138492
Protein Interaction Partner: APP, STX3, STX2, STX1A,
Protein Size: 134

Molecular Weight: 15 kDa

Gene ID: 10814

NCBI Accession: NM_006650, NP_006641

UniProt: Q6PUV4

Pathways: Synaptic Vesicle Exocytosis