PPIH antibody (Middle Region)

Catalog No. ABIN2784802

Product Details anti-PPIH Antibody

Target: PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Zebrafish (Danio rerio), Horse, Rabbit, Cow, Dog, Saccharomyces cerevisiae, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against PPIH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 177 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIH

Target: PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

Alternative Name: PPIH (PPIH Products)

Synonyms: CYP-20 antibody, CYPH antibody, SnuCyp-20 antibody, USA-CYP antibody, RGD1564921 antibody, cyp-20 antibody, cyph antibody, snucyp-20 antibody, usa-cyp antibody, PPIH antibody, zgc:136730 antibody, zgc:158595 antibody, zgc:55766 antibody, zgc:86780 antibody, 1100001J08Rik antibody, 2010111B15Rik antibody, 4833408F11Rik antibody, AI464484 antibody, D4Wsu43e antibody, peptidylprolyl isomerase H antibody, peptidylprolyl isomerase H (cyclophilin H) antibody, peptidylprolyl isomerase H L homeolog antibody, peptidyl prolyl isomerase H antibody, PPIH antibody, Ppih antibody, ppih antibody, ppih.L antibody

Background: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
Alias Symbols: CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP
Protein Interaction Partner: N4BP2L2, HUWE1, UBC, SOX2, METTL18, BAG2, PRPF4, VCAM1, ITGA4, FN1, PAXIP1, PCMT1, PRPF31, PPIH, PRPF3, NHP2L1, CUL3, Prpf8, MEPCE, USP15, SART3, USP4, PRPF18,
Protein Size: 177

Molecular Weight: 19 kDa

Gene ID: 10465

NCBI Accession: NM_006347, NP_006338

UniProt: O43447