NET1 antibody (N-Term)

Catalog No. ABIN2784784

Product Details anti-NET1 Antibody

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NET1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGDHRSPASA QKFSSRSTVP TPAKRRSSAL WSEMLDITMK ESLTTREIRR

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NET1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NET1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 542 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NET1

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Alternative Name: NET1 (NET1 Products)

Background: NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. It may be involved in activation of the SAPK/JNK pathway.
Alias Symbols: ARHGEF8, NET1A
Protein Interaction Partner: UBC, ELAVL1, MAGI1, DLG1, PRKAB2, USP11, RHOA,
Protein Size: 542

Molecular Weight: 62 kDa

Gene ID: 10276

NCBI Accession: NM_005863, NP_005854

UniProt: Q5SQI7

Pathways: Neurotrophin Signaling Pathway