ACTR1B antibody (Middle Region)
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- Target See all ACTR1B Antibodies
- ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACTR1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VGPARFRAPE LLFQPDLVGD ESEGLHEVVA FAIHKSDMDL RRTLFANIVL
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against ACTR1B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ACTR1B
- Top Product
- Discover our top product ACTR1B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 376 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
- Alternative Name
- ACTR1B (ACTR1B Products)
- Synonyms
- ARP1B antibody, CTRN2 antibody, PC3 antibody, 2310066K23Rik antibody, AA960180 antibody, AI851923 antibody, Arp1b antibody, ACTR1B antibody, ARP1 actin related protein 1 homolog B antibody, ARP1 actin-related protein 1B, centractin beta antibody, ARP1 actin-related protein 1 homolog B antibody, ARP1 actin-related protein 1 homolog B, centractin beta (yeast) antibody, beta-centractin antibody, ACTR1B antibody, Actr1b antibody, LOC100594459 antibody
- Background
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ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
Alias Symbols: ARP1B, CTRN2, PC3
Protein Interaction Partner: SEH1L, ACTR10, DCTN4, DCTN2, ACTR1A, RABEP1, LMNB1, DCTN3, APP, SMAD6, CUL3, UBC, TK1, MAPK6, CSNK2B, Dctn1, Capza1, CHD3, ACTA1,
Protein Size: 376 - Molecular Weight
- 42 kDa
- Gene ID
- 10120
- NCBI Accession
- NM_005735, NP_005726
- UniProt
- P42025
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