Adrenomedullin antibody (C-Term)
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- Target See all Adrenomedullin (ADM) Antibodies
- Adrenomedullin (ADM)
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Binding Specificity
- C-Term
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Reactivity
- Human, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Adrenomedullin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF
- Predicted Reactivity
- Human: 100%, Rabbit: 91%
- Characteristics
- This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ADM Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 185 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Adrenomedullin (ADM)
- Alternative Name
- ADM (ADM Products)
- Synonyms
- ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody
- Target Type
- Hormone
- Background
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Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
Alias Symbols: AM
Protein Interaction Partner: CALCRL, EDN1, CFH, MME, ADM,
Protein Size: 185 - Molecular Weight
- 20 kDa
- Gene ID
- 133
- NCBI Accession
- NM_001124, NP_001115
- UniProt
- P35318
- Pathways
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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