SLC47A2 antibody (C-Term)

Catalog No. ABIN2784682

Product Details anti-SLC47A2 Antibody

Target: SLC47A2 (Solute Carrier Family 47, Member 2 (SLC47A2))

Binding Specificity: C-Term

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC47A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TYSRSECHVD FFRTPEEAHA LSAPTSRLSV KQLVIRRGAA LGAASATLMV

Predicted Reactivity: Dog: 85%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC47A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC47A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 566 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC47A2 antibody (ABIN2784682)

Tanihara, Masuda, Sato, Katsura, Ogawa, Inui: "Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters." in: Biochemical pharmacology, Vol. 74, Issue 2, pp. 359-71, (2007) (PubMed).

Target Details for SLC47A2

Target: SLC47A2 (Solute Carrier Family 47, Member 2 (SLC47A2))

Alternative Name: SLC47A2 (SLC47A2 Products)

Synonyms: RGD1562382 antibody, MATE2 antibody, DKFZp469G161 antibody, SLC47A2 antibody, MATE2-B antibody, MATE2-K antibody, MATE2K antibody, 4933429E10Rik antibody, solute carrier family 47 member 1 antibody, solute carrier family 47 member 2 antibody, multidrug and toxin extrusion protein 2 antibody, solute carrier family 47, member 2 antibody, SLC47A1 antibody, Slc47a2 antibody, SLC47A2 antibody, MGYG_04899 antibody, LOC100020163 antibody, LOC100073163 antibody

Background: SLC47A2 is a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance.This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: FLJ31196, MATE2, MATE2-B, MATE2-K, MATE2K
Protein Size: 566

Molecular Weight: 61 kDa

Gene ID: 146802

NCBI Accession: NM_001099646, NP_001093116