CCT7 antibody (Middle Region)

Catalog No. ABIN2784636

Product Details anti-CCT7 Antibody

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Horse, Dog, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RAIKNDSVVA GGGAIEMELS KYLRDYSRTI PGKQQLLIGA YAKALEIIPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CCT7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCT7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 543 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT7

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Alternative Name: CCT7 (CCT7 Products)

Synonyms: Cct7 antibody, cct-eta antibody, ccth antibody, nip7-1 antibody, tcp-1-eta antibody, CCTETA antibody, CCTH antibody, NIP7-1 antibody, TCP1ETA antibody, CCT-ETA antibody, TCP-1-ETA antibody, AA408524 antibody, AL022769 antibody, Ccth antibody, Cctz antibody, chunp6934 antibody, fb38h02 antibody, fc05g05 antibody, wu:fb38h02 antibody, wu:fc05g05 antibody, chaperonin containing TCP1, subunit 7 (eta) antibody, chaperonin containing TCP1 subunit 7 antibody, chaperonin containing Tcp1, subunit 7 (eta) antibody, chaperonin containing TCP1 subunit 7 S homeolog antibody, Cct7 antibody, cct7 antibody, CCT7 antibody, cct7.S antibody

Background: CCT7 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.
Alias Symbols: CCT-ETA, Ccth, MGC110985, Nip7-1, TCP-1-eta, CCTH, CCTETA, NIP7-1, TCP1ETA
Protein Interaction Partner: SSSCA1, TP53, FUS, HUWE1, NEDD1, UBC, TUBG1, SUMO2, LGALS3BP, CDC20, MDM2, WWOX, ASB7, CCT3, CCT6A, PRPF40A, CCT5, CCT8, CCT2, CCT4, FBXO6, UBD, FBXW4, BAG3, HDAC6, HDAC3, ILK, CDK5, CDK2, AICDA, PAN2, METTL21B, VCAM1, FAM86B2, METTL18, PEX14, NOS2, NKX3-
Protein Size: 543

Molecular Weight: 60 kDa

Gene ID: 10574

NCBI Accession: NM_006429, NP_006420

UniProt: Q99832