INTS4 antibody (Middle Region)

Catalog No. ABIN2784574

Product Details anti-INTS4 Antibody

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PAEVVKILQT MLRQSAFLHL PLPEQIHKAS ATIIEPAGES DNPLRFTSGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against INTS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human INTS4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 963 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS4

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Alternative Name: INTS4 (INTS4 Products)

Synonyms: DDBDRAFT_0187061 antibody, DDBDRAFT_0234080 antibody, DDB_0187061 antibody, DDB_0234080 antibody, INT4 antibody, MST093 antibody, 2610034N24Rik antibody, AA692684 antibody, AW493223 antibody, RGD1305036 antibody, integrator complex subunit 4 antibody, HEAT repeat-containing protein antibody, ARM repeat superfamily protein antibody, integrator complex subunit 4 L homeolog antibody, CpipJ_CPIJ015422 antibody, ints4 antibody, NAEGRDRAFT_79682 antibody, INTS4 antibody, SIEL antibody, Ints4 antibody, ints4.L antibody

Background: INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].
Alias Symbols: INT4, MGC16733, MST093
Protein Interaction Partner: USHBP1, ZMIZ2, HGS, UBC, HECW2, INTS9, UBD, SUMO2, INTS10, SHFM1, INTS5, INTS3, INTS6, INTS1, RPAP2, KIAA0513,
Protein Size: 963

Molecular Weight: 108 kDa

Gene ID: 92105

NCBI Accession: NM_033547, NP_291025

UniProt: Q96HW7

Pathways: SARS-CoV-2 Protein Interactome