TBL1Y antibody (Middle Region)

Catalog No. ABIN2784572

Product Details anti-TBL1Y Antibody

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1Y antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LASGSFDKYV HIWNTQSGSL VHSYQGTGGI FEVCWNARGD KVGASASDGS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TBL1Y. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBL1Y

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 522 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBL1Y

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Alternative Name: TBL1Y (TBL1Y Products)

Synonyms: TBL1 antibody, transducin beta like 1, Y-linked antibody, TBL1Y antibody

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein.
Alias Symbols: TBL1
Protein Interaction Partner: SUZ12,
Protein Size: 522

Molecular Weight: 57 kDa

Gene ID: 90665

NCBI Accession: NM_033284, NP_150600

UniProt: Q9BQ87