HIST2H2AC antibody (Middle Region)
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- Target See all HIST2H2AC Antibodies
- HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HIST2H2AC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IPRHLQLAIR NDEELNKLLG KVTIAQGGVL PNIQAVLLPK KTESHKAKSK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HIST2H2AC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC
- Top Product
- Discover our top product HIST2H2AC Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 129 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
- Alternative Name
- HIST2H2AC (HIST2H2AC Products)
- Synonyms
- HIST2H2AC antibody, H2A antibody, H2A-GL101 antibody, H2A/q antibody, H2AFQ antibody, H2a-613b antibody, RGD1560965 antibody, histone cluster 1, H2A, IV antibody, histone cluster 2 H2A family member c antibody, histone cluster 2, H2ac antibody, HIST1H2A4 antibody, HIST2H2AC antibody, Hist2h2ac antibody
- Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A, H2A-GL101, H2A/q, H2AFQ, MGC74460
Protein Interaction Partner: BAP1, UBC, RNF2, INO80, UIMC1, RAD6, HDAC2, USP16, AURKB, NEDD8, CUL4A, USP15, SART3, HIST2H2BE, POLR2C, RNF168, HCVgp1, PRAME, RNF8, CRP, CENPA, HIST1H3B, EP300, KAT2A, BRCA1, BARD1, RBBP7, RBBP4, HAT1, ATXN7L3, USP22, MECP2, CHFR, DDB2, HIST1H4A, HIST1H
Protein Size: 129 - Molecular Weight
- 14 kDa
- Gene ID
- 8338
- NCBI Accession
- NM_003517, NP_003508
- UniProt
- Q16777
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