PPIA antibody (Middle Region)
-
- Target See all PPIA Antibodies
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Goat, Horse, Guinea Pig, Rabbit, Sheep
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PPIA antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PPIA
- Top Product
- Discover our top product PPIA Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 165 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
- Alternative Name
- PPIA (PPIA Products)
- Synonyms
- Cyp1 antibody, PPIA-2 antibody, fa93g09 antibody, ppia antibody, wu:fa93g09 antibody, wu:fb05e11 antibody, wu:fb13h02 antibody, wu:fb15a05 antibody, CYPA antibody, CypA antibody, Cypa antibody, CYPH antibody, CYCA antibody, CyP-A antibody, MGC75715 antibody, 2700098C05 antibody, Cphn antibody, CyP-18 antibody, MT-ND1 antibody, MTND1 antibody, NADH1 antibody, ND1 antibody, cypA antibody, PPIase A antibody, ppial antibody, wu:fj18g05 antibody, zgc:73102 antibody, zgc:86688 antibody, peptidylprolyl isomerase A antibody, peptidylprolyl isomerase Aa (cyclophilin A) antibody, peptidylprolyl isomerase A (cyclophilin A) L homeolog antibody, cyclophilin A antibody, cyclophilin a antibody, peptidylprolyl isomerase A (cyclophilin A) antibody, peptidylprolyl isomerase Ab (cyclophilin A) antibody, PPIA antibody, ppiaa antibody, ppia.L antibody, Cypa antibody, CNB01230 antibody, CNB01290 antibody, Tc00.1047053506925.300 antibody, Tb11.03.0250 antibody, CYPA antibody, Ppia antibody, ppia antibody, ppiab antibody
- Background
-
PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
Protein Size: 165 - Molecular Weight
- 18 kDa
- Gene ID
- 5478
- NCBI Accession
- NM_021130, NP_066953
- UniProt
- P62937
-