P2RY1 antibody (N-Term)

Catalog No. ABIN2784500

Product Details anti-P2RY1 Antibody

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against P2RY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 373 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-P2RY1 antibody (ABIN2784500)

Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: "Distribution and development of P2Y1-purinoceptors in the mouse retina." in: Journal of molecular histology, Vol. 44, Issue 6, pp. 639-44, (2013) (PubMed).

Target Details for P2RY1

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Alternative Name: P2RY1 (P2RY1 Products)

Synonyms: P2Y1 antibody, P2y antibody, P2y1 antibody, purinergic receptor P2Y, G-protein coupled 1 antibody, purinergic receptor P2Y1 antibody, P2ry1 antibody, P2RY1 antibody

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].
Alias Symbols: P2y1, P2Y1
Protein Interaction Partner: SLC9A3R2, SLC9A3R1, ADORA1,
Protein Size: 373

Molecular Weight: 42 kDa

Gene ID: 5028

NCBI Accession: NM_002563, NP_002554

UniProt: P47900

Pathways: Regulation of Carbohydrate Metabolic Process, Feeding Behaviour