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TNNT3 antibody (N-Term)

TNNT3 Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Dog, Goat, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784497
  • Target See all TNNT3 Antibodies
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Binding Specificity
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 27
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Dog, Goat, Zebrafish (Danio rerio)
    Host
    • 16
    • 9
    • 2
    Rabbit
    Clonality
    • 20
    • 7
    Polyclonal
    Conjugate
    • 21
    • 4
    • 1
    • 1
    This TNNT3 antibody is un-conjugated
    Application
    • 25
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3
    Top Product
    Discover our top product TNNT3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 250 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

    Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." in: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

  • Target
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Alternative Name
    TNNT3 (TNNT3 Products)
    Background
    Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
    Alias Symbols: AMCD2B, DA2B, DKFZp779M2348, FSSV, TNTF
    Protein Interaction Partner: TNNC1, TPM1, TNNI2, TNNC2, TNNT3, NUDT3, TSG101, TRIM63, SNUPN, HAP1,
    Protein Size: 250
    Molecular Weight
    30 kDa
    Gene ID
    7140
    NCBI Accession
    NM_001042780, NP_001036245
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