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TNNT3 antibody (N-Term)

TNNT3 Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog, Goat, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784497
  • Target See all TNNT3 Antibodies
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Binding Specificity
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog, Goat, Zebrafish (Danio rerio)
    Host
    • 28
    • 10
    • 2
    Rabbit
    Clonality
    • 32
    • 8
    Polyclonal
    Conjugate
    • 22
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNT3 antibody is un-conjugated
    Application
    • 31
    • 17
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3
    Top Product
    Discover our top product TNNT3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 250 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

    Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." in: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

  • Target
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Alternative Name
    TNNT3 (TNNT3 Products)
    Synonyms
    fTnT antibody, tnnt3a antibody, TNTF antibody, TnTf antibody, Tnt antibody, Tnnt3 antibody, troponin T3, fast skeletal type antibody, troponin T3, skeletal, fast antibody, troponin T3, fast skeletal type S homeolog antibody, troponin T type 3 (skeletal, fast) antibody, troponin T1, slow skeletal type antibody, TNNT3 antibody, Tnnt3 antibody, tnnt3.S antibody, TNNT1 antibody
    Background
    Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
    Alias Symbols: AMCD2B, DA2B, DKFZp779M2348, FSSV, TNTF
    Protein Interaction Partner: TNNC1, TPM1, TNNI2, TNNC2, TNNT3, NUDT3, TSG101, TRIM63, SNUPN, HAP1,
    Protein Size: 250
    Molecular Weight
    30 kDa
    Gene ID
    7140
    NCBI Accession
    NM_001042780, NP_001036245
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