TNNI2 antibody (N-Term)

Catalog No. ABIN2784492

Product Details anti-TNNI2 Antibody

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNI2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against TNNI2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 182 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TNNI2 antibody (ABIN2784492)

Wang, Luo, Sun, Deng, Li, Tao, Hu, Gong: "[Inhibitory effect of N-terminal 24 amino acids of the p55 gamma, a regulatory subunit of phosphoinositide 3-kinase, on proliferation of colon carcinoma cell line HT29]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 10, pp. 1034-8, (2008) (PubMed).

Target Details for TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Alternative Name: TNNI2 (TNNI2 Products)

Synonyms: AMCD2B antibody, DA2B antibody, FSSV antibody, fsTnI antibody, TnI-F4 antibody, TnI antibody, TNI antibody, hm:zehn0173 antibody, tnni2 antibody, tropI-1d antibody, zgc:86800 antibody, troponin I2, fast skeletal type antibody, troponin I type 2 (skeletal, fast) antibody, troponin I, fast skeletal muscle-like antibody, troponin I, skeletal, fast 2 antibody, troponin I type 2a (skeletal, fast), tandem duplicate 4 antibody, TNNI2 antibody, Tnni2 antibody, tnni2a.4 antibody

Background: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Alias Symbols: AMCD2B, DA2B, FSSV, fsTnI
Protein Interaction Partner: TRIM63, TRIM55, UPF2, RORB, HNF4G, ESRRA, PKD2L1, TNNC1, TNNC2, TNNT3, TNNT1, CALM1, ACTB,
Protein Size: 182

Molecular Weight: 21 kDa

Gene ID: 7136

NCBI Accession: NM_003282, NP_003273

UniProt: P48788